Disorders in the genes that control body temperature and its reaction to cold, can be one of the main causes of obesity, researchers found, published an article in the Journal of Neuroscience.
“Despite the fact that the body temperature in mice and humans differs, genes and receptors responsible for the recognition of cold and reaction to it are almost similar in humans and rodents. For this reason, we can say that changes in the structure of the TRPM8 gene can play a very important role in the development of obesity, what we did not know” — written by Alfonso Raimundez from the University of Santiago de Compostela (Spain) and his colleagues.
According to who, since the 1980-ies in the world there is a global obesity epidemic. Last year the extra pounds were suffering every third inhabitant of the planet (about 1.9 billion people), approximately 15 percent mentioned severe forms of pathology. While obesity is associated almost half of the disease — such as cardiovascular disease, diabetes and cancer.
In recent years, scientists are increasingly talking about the Association of obesity and chronic inflammatory processes. The extra pounds leads to the development of inflammatory foci, and this, in turn, leads to more weight gain. Moreover, recently biologists have found that substances that inhibit inflammation, e.g., capsaicin (the main component of the burning taste of pepper) — it turned out to be a very effective drug excess weight.