Scientists: pneumonia became immune to the “antibiotic of last resort”

Ученые: пневмония стала неуязвимой для "антибиотика последней надежды"

Some strains of pneumococcus that are present in U.S. hospitals, have become immune to the action of colistin, one of the “antibiotics of last resort” that will make pneumonia deadly disease in the near future, doctors say in an article published in the journal mBio.

“This is a very disturbing discovery as the pneumococci much more likely to cause infection than other bacteria. It is important to understand that in this case they were invincible and the action carbapenem, another antibiotic “of last resort”. With the development of real disease it would have forced clinicians to use colistin to fight infection. We never found pneumococci in the United States of this kind,” says David Weiss (David Weiss) from Emory University in Atlanta (USA).

In recent years, professionals are more and more it becomes a problem of occurrence of so-called “superbugs” – germs resistant to one or more antibiotics. Among them are rare pathogens and very common and dangerous pathogens, such as Staphylococcus aureus (Staphilococcus aureus) or Streptococcus pneumoniae (Klebsiella pneumoniae). There is a real danger that all antibiotics will lose their effectiveness and medicine back to the dark ages.

The main “incubators” of such microbes, as scientists believe today, are the hospitals and livestock farms, where antibiotics are used to accelerate the growth of beef cattle. And on farms, and in hospitals there are large number of potential infections, and the bacteria, and antibiotics, causing them to evolve and not giving a “normal” bacteria to crowd out less prolific superbugs.

Most of these “superbugs” is not yet fully immune to the effects of drugs – almost all of them can be destroyed using the so-called “antibiotics of last resort”, a relatively new drugs used only for medical purposes and only in the treatment of most serious infections. Thus, scientists are trying to “extend the life” of such drugs and to delay the moment when microbes become resistant to their effects.